Opportunity Information: Apply for PAR 18 767
The Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) opportunity (PAR 18-767) is a National Institutes of Health funding program led through the National Cancer Institute that supports long-term, structured partnerships between NCI-designated Cancer Centers (CCs) and institutions that serve underserved health disparity populations and educate underrepresented students (referred to as ISUPSs). It uses a cooperative agreement mechanism (U54), which typically means NIH program staff have an active role in overseeing and shaping the work as it progresses, rather than operating strictly as a hands-off grant. The overall intent is to strengthen the national cancer research enterprise while directly addressing persistent gaps in cancer outcomes, research participation, training access, and community benefit for populations that have historically been left out of cancer research and cancer-care advances. Clinical trials are optional under this announcement, meaning projects may include clinical trial activities when appropriate, but they are not required.
At the center of CPACHE is the idea that durable, mutually beneficial institutional partnerships can build capacity where it is most needed and can also make established cancer centers more effective in disparities-focused science. The program expects partners to work as a unified team to improve research infrastructure, training pipelines, mentorship, and community engagement in ways that last beyond the award period. Rather than funding isolated projects, CPACHE emphasizes comprehensive collaboration that integrates research, education, and outreach. In practice, this often translates into shared leadership and decision-making, coordinated cores or shared resources, cross-institutional mentoring teams, joint seminars and training activities, and collaborative research projects that are explicitly relevant to cancer inequities affecting surrounding communities.
The required goals of the partnership are clearly spelled out and cover four main areas. First, the partnership must increase cancer research and cancer research education capacity at the ISUPS institution(s). This can include strengthening faculty research capability, improving access to modern methods and technologies, expanding grant readiness, building sustainable mentorship networks, and enhancing educational offerings that prepare trainees to participate in competitive cancer research. Second, the program aims to increase the number of students and investigators from underrepresented populations who engage in cancer research, reflecting a workforce and pipeline objective that prioritizes recruitment, retention, training quality, and advancement. Third, CPACHE seeks to improve the ability of the NCI-designated Cancer Center to develop and sustain robust research programs focused on cancer health disparities, while also increasing the number of investigators and students (across the partnership) doing cancer disparities research. Fourth, the partnership must develop and implement cancer-related activities that provide tangible benefits to underserved communities, reinforcing that community impact is not an add-on but a core expectation. These community-oriented activities can include outreach, education, evidence-based interventions, research participation initiatives, navigation-related programming, or other locally responsive efforts that align with the partnership's strengths and the community's needs.
Eligibility for CPACHE is broad in terms of U.S.-based organizations, reflecting the program's interest in building cross-sector alliances that can sustain equity-focused work. Eligible applicants include multiple levels of government (state, county, city or township, special districts), independent school districts, public and private institutions of higher education, federally recognized tribal governments and other tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses) and small businesses, and other entities as allowed. The announcement also calls out categories of organizations that commonly align with the ISUPS role or community engagement role, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs). It also explicitly mentions faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and eligible federal agencies as potential applicants or partners, underscoring the flexibility to build partnerships that match local context and population needs.
There are clear restrictions related to foreign involvement. Non-domestic (non-U.S.) entities are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply under this opportunity. In addition, foreign components, as defined by the NIH Grants Policy Statement, are not allowed. In practical terms, the partnership and the supported activities must remain domestically based without foreign organizational components.
From an administrative standpoint, the opportunity is categorized under Education and Health, and it is associated with multiple CFDA numbers (93.393 through 93.399), reflecting its alignment with NCI programs across research, training, and related cancer initiatives. The funding instrument is a cooperative agreement, reinforcing that awardees should anticipate ongoing coordination with NIH staff, performance monitoring, and programmatic involvement consistent with U54 expectations. The original closing date listed for the provided record is January 11, 2021, and the source information does not specify an award ceiling or the expected number of awards, so those details would normally need to be confirmed through the full funding announcement or current NIH/NCI postings if the program is being reissued or continued under a related notice.
In short, CPACHE is designed to build sustained institutional partnerships that simultaneously (1) strengthen research and education capacity at institutions serving underserved and underrepresented groups, (2) grow and support a more diverse cancer research workforce, (3) deepen and expand cancer center leadership and productivity in cancer health disparities research, and (4) deliver meaningful cancer-focused benefits to underserved communities, all within a U.S.-based framework and with clinical trial participation available but not required.Apply for PAR 18 767
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Comprehensive Partnerships to Advance Cancer Health Equity (CPACHE) (Collaborative U54 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.393, 93.394, 93.395, 93.396, 93.397, 93.398, 93.399.
- This funding opportunity was created on 2018-04-30.
- Applicants must submit their applications by 2021-01-11. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Applicants who have applied for this opportunity (PAR 18 767) also looked into and applied for these:
| Funding Opportunity |
|---|
| Pilot and Feasibility Studies in Preparation for Drug and Alcohol Abuse Prevention Trials (R34 Clinical Trial Optional) Apply for PA 18 775 Funding Number: PA 18 775 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Pilot Health Services and Economic Research on the Treatment of Drug, Alcohol, and Tobacco Use Disorders (R34 Clinical Trial Optional) Apply for PA 18 774 Funding Number: PA 18 774 Agency: National Institutes of Health Category: Education, Health Funding Amount: $225,000 |
| Maternal Nutrition and Pre-pregnancy Obesity: Effects on Mothers, Infants and Children (R01 Clinical Trial Optional) Apply for PA 18 776 Funding Number: PA 18 776 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| International Research Collaboration on Drug Abuse and Addiction Research (R01 Clinical Trial Optional) Apply for PA 18 773 Funding Number: PA 18 773 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Investigation of the Transmission of Kaposi Sarcoma-Associated Herpesvirus (KSHV) (R21 Clinical Trial Not Allowed) Apply for RFA CA 18 014 Funding Number: RFA CA 18 014 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Investigation of the Transmission of Kaposi Sarcoma-associated Herpesvirus (KSHV)(R01 Clinical Trial Optional) Apply for RFA CA 18 013 Funding Number: RFA CA 18 013 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Precision Imaging of Oral Lesions (R01- Clinical Trial Not Allowed) Apply for PAR 18 787 Funding Number: PAR 18 787 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Genetic analysis of non-human animal models to understand the genomic architecture of substance use disorders and addictive behaviors (U01 Clinical Trial Not Allowed) Apply for PAR 18 789 Funding Number: PAR 18 789 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Computational Approaches to Curation at Scale for Biomedical Research Assets (R01 Clinical Trial Not Allowed) Apply for PAR 18 796 Funding Number: PAR 18 796 Agency: National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R41/R42 - Clinical Trial Optional) Apply for PAR 18 802 Funding Number: PAR 18 802 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Cancer Prevention, Diagnosis, and Treatment Technologies for Low-Resource Settings (R43/R44 - Clinical Trial Optional) Apply for PAR 18 801 Funding Number: PAR 18 801 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Administrative Supplements to Promote Diversity in Small Businesses-SBIR/STTR (Admin Supp Clinical Trial Not Allowed) Apply for PA 18 837 Funding Number: PA 18 837 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Collaborative Human Tissue Network (CHTN) (UM1 Clinical Trials Not Allowed) Apply for RFA CA 18 025 Funding Number: RFA CA 18 025 Agency: National Institutes of Health Category: Education, Health Funding Amount: $800,000 |
| Administrative Supplements to Support Cancer Disparity Collaborative Research (Clinical Trial Optional) Apply for PA 18 842 Funding Number: PA 18 842 Agency: National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Oncology Co-Clinical Imaging Research Resources to Encourage Consensus on Quantitative Imaging Methods and Precision Medicine (U24 - Clinical Trial Optional) Apply for PAR 18 841 Funding Number: PAR 18 841 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Prevention Research (R01 - Clinical Trial Optional) Apply for PAR 18 847 Funding Number: PAR 18 847 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Electronic Nicotine Delivery Systems (ENDS): Population, Clinical and Applied Prevention Research (R21 - Clinical Trial Optional) Apply for PAR 18 848 Funding Number: PAR 18 848 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Prevention Research in Mid-Life Adults (R01 Clinical Trial Optional) Apply for PA 18 849 Funding Number: PA 18 849 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Prevention Research in Mid-Life Adults (R21 Clinical Trial Optional) Apply for PA 18 850 Funding Number: PA 18 850 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Administrative Supplements to Promote Collaborative Activities in Basic Cancer Research (Admin Supp - Clinical Trial Not Allowed) Apply for PA 18 852 Funding Number: PA 18 852 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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