Opportunity Information: Apply for HRSA 25 065

The Ending the HIV Epidemic in the U.S. - Systems Coordination Provider (SCP) grant opportunity (HRSA-25-065) is a federal funding announcement from the Health Resources and Services Administration (HRSA), specifically through HRSA's HIV/AIDS Bureau (HAB), working alongside the Ryan White HIV/AIDS Program (RWHAP) Parts A and B. The overall intent is to support the national Ending the HIV Epidemic (EHE) initiative by strengthening how EHE-funded jurisdictions plan, align, and coordinate HIV care and treatment efforts so that federal, state, and local resources work together rather than in parallel. This opportunity is paired with a related announcement for a Technical Assistance Provider (TAP) (HRSA-25-064). HRSA expects to make a single award under HRSA-25-065, and the award mechanism is a cooperative agreement, which generally means HRSA will have substantial involvement with the awardee during the project period rather than acting only as a pass-through funder.

The SCP's work is designed to support a defined set of EHE jurisdictions that were originally identified and funded under HRSA-20-078, including 48 counties, Washington, D.C., San Juan, Puerto Rico, and seven states. In this structure, those jurisdictions are the on-the-ground "recipients" implementing EHE activities under a separate award (referenced here as HRSA-25-063). The EHE initiative has four national strategies: diagnose people with HIV as early as possible, treat people with HIV rapidly and effectively to achieve sustained viral suppression, prevent new transmissions using proven interventions like PrEP and syringe services programs, and respond quickly to potential outbreaks. HRSA HAB's lane in this broader federal effort, and the emphasis for recipients supported under HRSA-25-063, is mainly on the "Treat" and "Respond" pillars, meaning rapid linkage to care, sustained engagement and retention in care, and outbreak-response capacity connected to clinical care and treatment systems.

Within that landscape, the Systems Coordination Provider is essentially the "glue" role. The SCP is expected to help EHE jurisdictions integrate their EHE plans, funding streams, and program activities with the existing HIV care delivery infrastructure, especially the Ryan White Part A and Part B systems already operating in those areas. The need for this role is driven by the reality that EHE jurisdictions often have multiple new or expanded federal resources arriving at the same time as longstanding HIV funding sources, and without active coordination those resources can become fragmented, duplicative, or misaligned. The SCP is meant to reduce that friction by supporting shared planning, clarifying how different funds and programs complement each other, encouraging consistent approaches across systems, and helping jurisdictions get maximum impact from the full mix of available resources.

A core part of the SCP function is stakeholder coordination. The announcement emphasizes helping recipients identify both existing and new stakeholders who should be engaged in EHE implementation, which in practice can include public health departments, Ryan White planning councils, clinical providers, community-based organizations, behavioral health and substance use partners, correctional health systems, Medicaid agencies and managed care organizations, and other local decision-makers who influence access to HIV care and treatment. By helping bring these groups into a more organized coordination structure, the SCP supports smoother implementation of interventions intended to improve linkage to care, engagement, and retention, including emerging, evidence-informed, and evidence-based approaches that jurisdictions choose to adopt with their HRSA-25-063 funds.

The SCP is also positioned as a dissemination hub that works alongside the separately funded Technical Assistance Provider. While the TAP (HRSA-25-064) focuses on providing direct technical assistance to jurisdictions on implementing work plan activities, innovations, and interventions, the SCP is expected to take what is learned from those efforts and help spread it. Specifically, the SCP will collate and disseminate best practices, innovative approaches, and effective interventions identified by the TAP, so jurisdictions can learn from one another and scale what works more quickly. In other words, the TAP helps recipients do the work better at the implementation level, and the SCP helps ensure the overall system and network of partners stay aligned while good ideas and proven approaches travel across jurisdictions instead of staying isolated.

In terms of eligibility, HRSA allows a broad range of domestic applicants. Eligible applicant types include state, county, and city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; nonprofits with or without 501(c)(3) status; for-profit organizations (including small businesses); federally recognized Native American tribal governments; and other Native American tribal organizations. "Domestic" is defined broadly to include the 50 states, the District of Columbia, Puerto Rico, other U.S. territories, and the freely associated states listed in the announcement. The opportunity is categorized as discretionary funding, the activity category is health, and the CFDA number listed is 93.145. The original application closing date is October 22, 2024. The posting indicates an expected number of awards of one, and although an award ceiling is listed as 0 in the provided source data, that typically signals that the ceiling is either not specified in that field or is described elsewhere in the full notice rather than meaning no funding is available.

Taken together, HRSA-25-065 is less about delivering direct clinical services and more about making sure clinical and public health systems can operate as a coordinated whole in EHE jurisdictions. The end goal is to help jurisdictions make faster progress on treatment outcomes and rapid response, which supports the broader national aim of reducing new HIV infections in the United States by improving how people are linked to care, kept in care, and supported to reach and maintain viral suppression, while ensuring all the moving parts of HIV funding and programming are pulling in the same direction.

  • The Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Ending the HIV Epidemic in the U.S. – Systems Coordination Provider" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.145.
  • This funding opportunity was created on 2024-08-22.
  • Applicants must submit their applications by 2024-10-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 1 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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